Clinical trials help to advance medical knowledge and discover better ways to prevent, treat, or improve the care of patients with cancer. Many people treated for cancer are now living longer thanks to the medical heroes who have participated in clinical trials. Taking an active part in your cancer treatment by participating in a clinical trial is an empowering experience, as you help to improve the care and treatment for all and pave the way for a better tomorrow.

Cancer Research Study


Alternate Approaches for Clinical Stage II or III Estrogen Receptor Positive Breast Cancer Neoadjuvant Treatment (ALTERNATE) in Postmenopausal Women:
A Phase III Study

Why the study is being done/Purpose:
PURPOSE: This randomized phase III trial has several primary objectives. One primary objective is to compare the efficacy of 3 different endocrine therapies, the estrogen receptor down regulator fulvestrant and the aromatase inhibitor anastrozole, either alone or in combination, in reducing cancer growth before surgery (neoadjuvant) in postmenopausal women with clinical stage II-III estrogen receptor positive and HER2 negative breast cancer. Another primary objective is to evaluate whether patients who achieved a modified PEPI (Preoperative Endocrine Prognostic Index) score of 0, defined by tumor size <5 cm, N0, Ki67<2.7% (by central testing), at surgery post 6 months of neoadjuvant endocrine therapy predict excellent long term outcome, for whom chemotherapy is unnecessary. [FOR MORE]

Learn More About Our Treatment Research Activity

Staying up to date with the newest trends in cancer treatment research is crucial. Our doctors take great care in participating in the latest research so that we can continue to offer you the latest in care.

Cancer Trials Support Unit

The Cancer Trials Support Unit (CTSU) is a project sponsored by the National Cancer Institute (NCI) for the support of a national network of physicians to participate in NCI-sponsored Phase III cancer treatment trials.

Staying up to Date on the Latest Clinical Trials

By participating in clinical trials, we are able to offer alternative treatment paths to those in need while providing an opportunity for much needed research into new technology and practices.

Read More about Our Individual Studies

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Vineland, New Jersey

Salem, New Jersey

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Southern Oncology Hematology Associates
1505 W Sherman Ave Ste 101
Vineland, New Jersey 08360
Tel: 856-696-9550

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